Identification of Circulating Human Antigen-Reactive CD4+FOXP3+ Natural Regulatory T Cells
نویسندگان
چکیده
منابع مشابه
Identification of circulating human antigen-reactive CD4+ FOXP3+ natural regulatory T cells.
Circulating human CD4(+)CD25(++)CD127(-)FOXP3(+) T cells with a persistent demethylated regulatory T cell (Treg)-specific demethylated region Foxp3 gene are considered natural Tregs (nTregs). We have shown that it is possible to identify functional Ag-reactive nTregs cells for a range of different common viral and vaccination Ags. The frequency of these Ag-reactive nTregs within the nTreg popul...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2011
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.1101974